BDBM50152305 Biphenyl-4-carboxylic acid (1-benzyl-pyrrolidin-3-yl)-amide::CHEMBL185156

SMILES O=C(NC1CCN(Cc2ccccc2)C1)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=LTDTVIVWGGLMSW-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50152305   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152305(Biphenyl-4-carboxylic acid (1-benzyl-pyrrolidin-3-...)
Affinity DataKi:  3nMAssay Description:Ability to displace [3H]-spiperone from human Dopamine receptor D4.2 stably transfected in human embryonic kidney 298 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152305(Biphenyl-4-carboxylic acid (1-benzyl-pyrrolidin-3-...)
Affinity DataKi:  600nMAssay Description:Ability to displace [3H]-spiperone from human Dopamine receptor D2S stably transfected in GH4C1 (rat pituitary) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152305(Biphenyl-4-carboxylic acid (1-benzyl-pyrrolidin-3-...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibitory concentration required to reverse the dopamine inhibition of forskolin-stimulated adenyl cyclase activity in CHO cells stably expressing h...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed