BDBM50152377 4-[4-(N-Substituted-thio-carbamoyl)-1-piperazinyl]-6-methoxy-7-alkoxyamino-quinazoline derivative::CHEMBL186850

SMILES COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(NCc1ccc2OCOc2c1)=NC#N

InChI Key InChIKey=KQGFBLYLLXKIPF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152377   

TargetPlatelet-derived growth factor receptor beta(Human)
In Vivo Sciences Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152377(4-[4-(N-Substituted-thio-carbamoyl)-1-piperazinyl]...)
Affinity DataIC50: 320nMAssay Description:In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells without plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
In Vivo Sciences Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50152377(4-[4-(N-Substituted-thio-carbamoyl)-1-piperazinyl]...)
Affinity DataIC50: 590nMAssay Description:In vitro inhibition of Platelet derived growth factor receptor beta autophosphorylation in MG-63 cells with 45% human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed