BDBM50152513 CHEMBL361457::[2-Methyl-1-(4-phenethyloxy-benzoyl)-1H-indol-4-yl]-acetic acid

SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCCc2ccccc2)cc1

InChI Key InChIKey=JLYOJYCKWIZTAQ-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50152513   

TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152513(CHEMBL361457 | [2-Methyl-1-(4-phenethyloxy-benzoyl...)
Affinity DataKi:  1.80nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152513(CHEMBL361457 | [2-Methyl-1-(4-phenethyloxy-benzoyl...)
Affinity DataKi:  400nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152513(CHEMBL361457 | [2-Methyl-1-(4-phenethyloxy-benzoyl...)
Affinity DataKi:  1.30E+3nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152513(CHEMBL361457 | [2-Methyl-1-(4-phenethyloxy-benzoyl...)
Affinity DataKi:  1.90E+3nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152513(CHEMBL361457 | [2-Methyl-1-(4-phenethyloxy-benzoyl...)
Affinity DataKi:  2.20E+3nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Mus musculus)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152513(CHEMBL361457 | [2-Methyl-1-(4-phenethyloxy-benzoyl...)
Affinity DataIC50:  120nMAssay Description:Effect on the increase in cAMP formation induced by PGD-2 in the presence of bovine serum albumin in CHO cells expressing mouse Prostaglandin D2 rece...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed