BDBM50152523 CHEMBL180528::[(S)-5-[(Morpholine-4-carbonyl)-amino]-1-((R)-1-phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-(4-fluoro-benzyl)-cyclobutylmethyl ester

SMILES C[C@@H](NC(=O)C(=O)[C@H](CCCCNC(=O)N1CCOCC1)NC(=O)OCC1(Cc2ccc(F)cc2)CCC1)c1ccccc1

InChI Key InChIKey=BSRQMYCWEZBYDT-YWEHKCAJSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50152523   

TargetPro-cathepsin H(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152523(CHEMBL180528 | [(S)-5-[(Morpholine-4-carbonyl)-ami...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of 50 uM L-Arg-beta-naphthalamide binding to human cathepsin H in fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152523(CHEMBL180528 | [(S)-5-[(Morpholine-4-carbonyl)-ami...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of 10 uM Cbz-Phe-Arg-AMC binding to human cathepsin B in fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152523(CHEMBL180528 | [(S)-5-[(Morpholine-4-carbonyl)-ami...)
Affinity DataIC50:  27nMAssay Description:Inhibition of 10 uM Cbz-Val-Val-Arg-AMC binding to human cathepsin S in fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152523(CHEMBL180528 | [(S)-5-[(Morpholine-4-carbonyl)-ami...)
Affinity DataIC50:  680nMAssay Description:Inhibition of 5 uM Cbz-Phe-Arg-AMC human cathepsin L in fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152523(CHEMBL180528 | [(S)-5-[(Morpholine-4-carbonyl)-ami...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed