BDBM50152550 4-(2,6-Dichloro-phenyl)-2,4-dioxo-butyric acid::CHEMBL185070

SMILES c1cc(c(c(c1)Cl)C(=O)CC(=O)C(=O)O)Cl

InChI Key InChIKey=JNJNEAZUJSUZGZ-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152550   

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50152550(4-(2,6-Dichloro-phenyl)-2,4-dioxo-butyric acid | C...)
Affinity DataIC50: 3.79E+4nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA excision repair protein ERCC-5(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50152550(4-(2,6-Dichloro-phenyl)-2,4-dioxo-butyric acid | C...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed