BDBM50152575 2,4-Dioxo-4-o-tolyl-butyric acid::CHEMBL1829214::CHEMBL185898::Sacchettini_1

SMILES: Cc1ccccc1C(=O)CC(=O)C(=O)O

InChI Key: InChIKey=AVVYWVLNDGDANA-UHFFFAOYSA-N

Data: 1 KI  3 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50152575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Malate synthase G [C619A] (Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)	BDBM50152575 (CHEMBL1829214 | CHEMBL185898 | 2,4-Dioxo-4-o-tolyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA excision repair protein ERCC-5 (Human)	BDBM50152575 (CHEMBL1829214 | CHEMBL185898 | 2,4-Dioxo-4-o-tolyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Flap endonuclease 1 (Human)	BDBM50152575 (CHEMBL1829214 | CHEMBL185898 | 2,4-Dioxo-4-o-tolyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polymerase acidic protein (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)	BDBM50152575 (CHEMBL1829214 | CHEMBL185898 | 2,4-Dioxo-4-o-tolyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polymerase acidic protein (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)	BDBM50152575 (CHEMBL1829214 | CHEMBL185898 | 2,4-Dioxo-4-o-tolyl...) Show SMILES Show InChI	GoogleScholar	UniChem		2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair