BDBM50152901 1-Methyl-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-pyrrolidine-3-carboxylic acid hydroxyamide::CHEMBL184885::N-hydroxy-1-methyl-2-((4-((2-methylquinolin-4-yl)methoxy)phenylsulfonyl)methyl)pyrrolidine-3-carboxamide

SMILES CN1CCC(C1CS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO

InChI Key InChIKey=QPQUYVHWOXJEPM-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50152901   

TargetCollagenase 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152901(1-Methyl-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benz...)
Affinity DataKi:  1.71E+3nMAssay Description:Inhibition of Matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152901(1-Methyl-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benz...)
Affinity DataKi: >2.10E+3nMAssay Description:Inhibition of Matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152901(1-Methyl-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benz...)
Affinity DataKi: >3.30E+3nMAssay Description:inhibition of Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152901(1-Methyl-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benz...)
Affinity DataKi: >4.90E+3nMAssay Description:Inhibition of Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50152901(1-Methyl-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benz...)
Affinity DataIC50:  1nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50152901(1-Methyl-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benz...)
Affinity DataIC50: <1nMAssay Description:Inhibition of porcine Tumor necrosis factor- alpha converting enzyme (TACE, ADAM17)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
The M. S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50152901(1-Methyl-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benz...)
Affinity DataIC50:  180nMAssay Description:Effect on TNF-Alpha release in LPS-stimulated human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed