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BDBM50153202 CHEMBL186491::N-(2-Diethylamino-ethyl)-2-methoxy-4-(4-phenoxy-benzoylamino)-benzamide

SMILES: CCN(CC)CCNC(=O)c1ccc(NC(=O)c2ccc(Oc3ccccc3)cc2)cc1OC

InChI Key: InChIKey=IZGYVBOGCUZDNQ-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153202   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM50153202
PNG
(CHEMBL186491 | N-(2-Diethylamino-ethyl)-2-methoxy-...)
Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)c2ccc(Oc3ccccc3)cc2)cc1OC
Show InChI InChI=1S/C27H31N3O4/c1-4-30(5-2)18-17-28-27(32)24-16-13-21(19-25(24)33-3)29-26(31)20-11-14-23(15-12-20)34-22-9-7-6-8-10-22/h6-16,19H,4-5,17-18H2,1-3H3,(H,28,32)(H,29,31)
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GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.81E+3n/an/an/an/an/an/a



7TM Pharma A/S

Curated by ChEMBL


Assay Description
Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assay


Bioorg Med Chem Lett 14: 5075-80 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.077
BindingDB Entry DOI: 10.7270/Q2CF9PKT
More data for this
Ligand-Target Pair
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM50153202
PNG
(CHEMBL186491 | N-(2-Diethylamino-ethyl)-2-methoxy-...)
Show SMILES CCN(CC)CCNC(=O)c1ccc(NC(=O)c2ccc(Oc3ccccc3)cc2)cc1OC
Show InChI InChI=1S/C27H31N3O4/c1-4-30(5-2)18-17-28-27(32)24-16-13-21(19-25(24)33-3)29-26(31)20-11-14-23(15-12-20)34-22-9-7-6-8-10-22/h6-16,19H,4-5,17-18H2,1-3H3,(H,28,32)(H,29,31)
Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.97E+3n/an/an/an/an/an/a



7TM Pharma A/S

Curated by ChEMBL


Assay Description
Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand


Bioorg Med Chem Lett 14: 5075-80 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.077
BindingDB Entry DOI: 10.7270/Q2CF9PKT
More data for this
Ligand-Target Pair