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BDBM50153243 Biphenyl-4-carboxylic acid [4-(2-dimethylamino-ethylcarbamoyl)-phenyl]-amide::CHEMBL186601

SMILES: CN(C)CCNC(=O)c1ccc(NC(=O)c2ccc(cc2)-c2ccccc2)cc1

InChI Key: InChIKey=AJQUGUQYKMEIFI-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50153243   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM50153243
PNG
(Biphenyl-4-carboxylic acid [4-(2-dimethylamino-eth...)
Show SMILES CN(C)CCNC(=O)c1ccc(NC(=O)c2ccc(cc2)-c2ccccc2)cc1
Show InChI InChI=1S/C24H25N3O2/c1-27(2)17-16-25-23(28)20-12-14-22(15-13-20)26-24(29)21-10-8-19(9-11-21)18-6-4-3-5-7-18/h3-15H,16-17H2,1-2H3,(H,25,28)(H,26,29)
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Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



7TM Pharma A/S

Curated by ChEMBL


Assay Description
Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]-MCH as radioligand


Bioorg Med Chem Lett 14: 5075-80 (2004)


Article DOI: 10.1016/j.bmcl.2004.07.077
BindingDB Entry DOI: 10.7270/Q2CF9PKT
More data for this
Ligand-Target Pair