BDBM50153707 CHEMBL3775824

SMILES CC(C)CN1CCc2cc(O)ccc2[C@H]1c1ccc(\C=C\C(O)=O)cc1

InChI Key InChIKey=PRJBEVDNTURUGU-YHEXHBFFSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50153707   

TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153707(CHEMBL3775824)
Affinity DataIC50:  4.40nMAssay Description:Downregulation of ERalpha in human MCF7 cells incubated for 18 to 22 hrs by immunofluorescence assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153707(CHEMBL3775824)
Affinity DataIC50:  4nMAssay Description:Induction of ERalpha degradation in human MCF7 cells after 18 to 24 hrs by in multiplexed cell assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153707(CHEMBL3775824)
Affinity DataIC50:  25nMAssay Description:Binding affinity to recombinant human GST-tagged ERalpha LBD expressed in baculovirus-infected insect cells by lantha screen assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153707(CHEMBL3775824)
Affinity DataIC50:  26nMAssay Description:Displacement of fluormone ES2 from GST-tagged recombinant human ERalpha LBD after 1 hr by Lanthascreen TR-FRET assayMore data for this Ligand-Target Pair