BDBM50154037 2-Amino-3-(4-hydroxy-phenyl)-1-[2-(5-methyl-4-phenyl-1H-imidazol-2-yl)-pyrrolidin-1-yl]-propan-1-one::CHEMBL186527

SMILES Cc1[nH]c(nc1-c1ccccc1)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1

InChI Key InChIKey=WTLPGZMNWBXIHT-PMACEKPBSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50154037   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154037(2-Amino-3-(4-hydroxy-phenyl)-1-[2-(5-methyl-4-phen...)
Affinity DataKi:  23nMAssay Description:Binding affinity for Mu opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154037(2-Amino-3-(4-hydroxy-phenyl)-1-[2-(5-methyl-4-phen...)
Affinity DataKi: >100nMAssay Description:Binding affinity for delta opioid receptor of rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50154037(2-Amino-3-(4-hydroxy-phenyl)-1-[2-(5-methyl-4-phen...)
Affinity DataEC50:  1.30E+3nMAssay Description:Inhibition of mu opioid receptor mediated GTPgammaS binding to CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed