BDBM50154048 3-(5-Hydroxy-naphthalen-1-yl)-benzo[d]isoxazol-6-ol::3-(5-hydroxynaphthalen-1-yl)benzo[d]isoxazol-6-ol::CHEMBL188051

SMILES Oc1ccc2c(noc2c1)-c1cccc2c(O)cccc12

InChI Key InChIKey=UYBIVRLEZVLKDU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50154048   

TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154048(3-(5-Hydroxy-naphthalen-1-yl)-benzo[d]isoxazol-6-o...)
Affinity DataIC50:  1.5nMAssay Description:Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154048(3-(5-Hydroxy-naphthalen-1-yl)-benzo[d]isoxazol-6-o...)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity to ERbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154048(3-(5-Hydroxy-naphthalen-1-yl)-benzo[d]isoxazol-6-o...)
Affinity DataIC50:  6nMAssay Description:Inhibitory concentration against human ER alpha expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed