BDBM50154110 5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carbaldehyde::5-hydroxy-2-(4-hydroxyphenyl)benzo[d]oxazole-7-carbaldehyde::CHEMBL188230

SMILES Oc1ccc(cc1)-c1nc2cc(O)cc(C=O)c2o1

InChI Key InChIKey=RVKNUINNULNHGO-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50154110   

TargetEstrogen receptor beta(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154110(5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carb...)
Affinity DataIC50:  17nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to mouse ER beta expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154110(5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carb...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to mouse ER alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154110(5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carb...)
Affinity DataIC50:  59nMAssay Description:Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154110(5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carb...)
Affinity DataIC50:  59nMAssay Description:Binding affinity to ERbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154110(5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carb...)
Affinity DataIC50:  2.64E+3nMAssay Description:Inhibitory concentration against human ER alpha expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154110(5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carb...)
Affinity DataIC50:  29nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to rat ER beta expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(RAT)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154110(5-Hydroxy-2-(4-hydroxy-phenyl)-benzooxazole-7-carb...)
Affinity DataIC50:  2.25E+3nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to rat ER alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed