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BDBM50155043 3''-(5-Pyridin-2-yl-tetrazol-2-yl)-biphenyl-3-carboxylic acid methyl ester::CHEMBL184821

SMILES: COC(=O)c1cccc(c1)-c1cccc(c1)-n1nnc(n1)-c1ccccn1

InChI Key: InChIKey=ILOOTZLWHQGCRZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50155043   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))
BDBM50155043
PNG
(3''-(5-Pyridin-2-yl-tetrazol-2-yl)-biphenyl-3-carb...)
Show SMILES COC(=O)c1cccc(c1)-c1cccc(c1)-n1nnc(n1)-c1ccccn1
Show InChI InChI=1S/C20H15N5O2/c1-27-20(26)16-8-4-6-14(12-16)15-7-5-9-17(13-15)25-23-19(22-24-25)18-10-2-3-11-21-18/h2-13H,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 337n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro antagonistic activity against Metabotropic glutamate receptor 5 in [Ca2+] flux assay


Bioorg Med Chem Lett 14: 5485-8 (2004)


Article DOI: 10.1016/j.bmcl.2004.09.016
BindingDB Entry DOI: 10.7270/Q21V5DGP
More data for this
Ligand-Target Pair