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BDBM50155290 CHEMBL3774656

SMILES: Cc1nc2ccccc2n(CC(=O)N\N=C\c2ccc(Cl)cc2)c1=O

InChI Key: InChIKey=UVGJFCXWQQUFEY-KEBDBYFISA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155290   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50155290
PNG
(CHEMBL3774656)
Show SMILES Cc1nc2ccccc2n(CC(=O)N\N=C\c2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C18H15ClN4O2/c1-12-18(25)23(16-5-3-2-4-15(16)21-12)11-17(24)22-20-10-13-6-8-14(19)9-7-13/h2-10H,11H2,1H3,(H,22,24)/b20-10+
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.49E+5n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of porcine microsomal aminopeptidase N preincubated for 30 mins using L-Leu-p-nitroanilide as substrate by UV-VIS spectrophotometer


Bioorg Med Chem 24: 2125-36 (2016)


Article DOI: 10.1016/j.bmc.2016.03.043
BindingDB Entry DOI: 10.7270/Q28S4RSZ
More data for this
Ligand-Target Pair
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM50155290
PNG
(CHEMBL3774656)
Show SMILES Cc1nc2ccccc2n(CC(=O)N\N=C\c2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C18H15ClN4O2/c1-12-18(25)23(16-5-3-2-4-15(16)21-12)11-17(24)22-20-10-13-6-8-14(19)9-7-13/h2-10H,11H2,1H3,(H,22,24)/b20-10+
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.10E+4n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of gelatinase A (unknown origin) after 30 mins using succinylated gelatin as substrate


Bioorg Med Chem 24: 2125-36 (2016)


Article DOI: 10.1016/j.bmc.2016.03.043
BindingDB Entry DOI: 10.7270/Q28S4RSZ
More data for this
Ligand-Target Pair