BDBM50155311 CHEMBL3781301

SMILES Oc1cccc(CN(CCN2CCCCC2)CC2CCCN(C2)C2CCCC2)c1

InChI Key InChIKey=BOGRGBJASHXDLV-DOTOQJQBSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50155311   

TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50155311(CHEMBL3781301)
Affinity DataEC50:  1.90E+3nMAssay Description:Antagonist activity at CXCR4 expressed in human U373-MAGI cells assessed as inhibition of HIV1 gp120-induced cell-cell fusion between HIV1 NL4-3 enve...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50155311(CHEMBL3781301)
Affinity DataIC50:  9.20E+4nMAssay Description:Inhibition of human recombinant CXCR4 expressed in THP-1 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50155311(CHEMBL3781301)
Affinity DataIC50:  92nMAssay Description:Antagonist activity at CXCR4 in human MOLT-4 cells assessed as decrease in SDF-1alpha induced cytosolic Ca2+ levels preincubated for 30 mins followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50155311(CHEMBL3781301)
Affinity DataIC50:  92nMAssay Description:Antagonist activity against CXCR4 in in human MOLT4 cells assessed as inhibition of SDF1alpha -induced Ca2+ mobilization after 30 mins by FACS analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed