BDBM50156082 CHEMBL362969::N-(4-bromo-2-((1,3-dioxoisoindolin-2-yl)methyl)phenyl)picolinamide::Pyridine-2-carboxylic acid [4-bromo-2-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-phenyl]-amide

SMILES Brc1ccc(NC(=O)c2ccccn2)c(CN2C(=O)c3ccccc3C2=O)c1

InChI Key InChIKey=JGXUCEXYUKMDKB-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50156082   

TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merck

Curated by ChEMBL
LigandPNGBDBM50156082(CHEMBL362969 | N-(4-bromo-2-((1,3-dioxoisoindolin-...)
Affinity DataEC50: <1.00E+3nMAssay Description:Activity at rat mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50156082(CHEMBL362969 | N-(4-bromo-2-((1,3-dioxoisoindolin-...)
Affinity DataEC50:  750nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50156082(CHEMBL362969 | N-(4-bromo-2-((1,3-dioxoisoindolin-...)
Affinity DataEC50:  740nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed