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BDBM50156204 CHEMBL3780141

SMILES: COc1ccc(cc1N1CCNCC1)S(=O)(=O)NCC(C)(C)c1cccc2ccccc12

InChI Key: InChIKey=LEIQNIXFPZRVQZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50156204   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50156204
PNG
(CHEMBL3780141)
Show SMILES COc1ccc(cc1N1CCNCC1)S(=O)(=O)NCC(C)(C)c1cccc2ccccc12
Show InChI InChI=1S/C25H31N3O3S/c1-25(2,22-10-6-8-19-7-4-5-9-21(19)22)18-27-32(29,30)20-11-12-24(31-3)23(17-20)28-15-13-26-14-16-28/h4-12,17,26-27H,13-16,18H2,1-3H3
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.30n/an/an/an/an/an/a



Temple University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5-HT6 receptor expressed in CHO cell membranes after 120 mins by liquid scintillation counting method


ACS Med Chem Lett 7: 12-4 (2016)


Article DOI: 10.1021/acsmedchemlett.5b00466
BindingDB Entry DOI: 10.7270/Q2Z89F8F
More data for this
Ligand-Target Pair