BDBM50156517 (1S,6R,7S)-4-(4-Cyano-3-trifluoromethyl-phenyl)-6-methyl-3,5-dioxo-2,4,8-triaza-tricyclo[5.2.1.0*2,6*]decane-8-carboxylic acid tert-butyl ester::CHEMBL188261

SMILES CC(C)(C)OC(=O)N1C[C@@H]2C[C@H]1[C@@]1(C)N2C(=O)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=BOROTNFLIVKJEO-ZQGRQUNCSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50156517   

TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156517((1S,6R,7S)-4-(4-Cyano-3-trifluoromethyl-phenyl)-6-...)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]-DHT from androgen receptor of human MDA-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156517((1S,6R,7S)-4-(4-Cyano-3-trifluoromethyl-phenyl)-6-...)
Affinity DataIC50:  1.04E+4nMAssay Description:In vitro antagonistic activity against mutant androgen receptor of LNCap cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156517((1S,6R,7S)-4-(4-Cyano-3-trifluoromethyl-phenyl)-6-...)
Affinity DataIC50:  780nMAssay Description:In vitro antagonistic activity against androgen receptor of MDA-453 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed