BDBM50156760 (E)-2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-phenylethyl)benzamide::2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-phenylethyl)benzamide::2-{[(1-(2-hydroxy-naphthalen-1-yl)meth-(E)-ylidene]amino}-N-(1-phenylethyl)-benzamide::2-{[1-(2-hydroxynaphthalen-1-yl)meth-(E)-ylene]amino}-N-(1-phenylethyl)benzamide::CHEMBL380797::Sirtinol

SMILES: CC(NC(=O)c1ccccc1\N=C\c1c(O)ccc2ccccc12)c1ccccc1

InChI Key: InChIKey=UXJFDYIHRJGPFS-UHFFFAOYSA-N

Data: 38 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 40 hits for monomerid = 50156760   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase HST2 (Baker's yeast)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacylase sirtuin-5, mitochondrial (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.23E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacylase sirtuin-5, mitochondrial (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.01E+4	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase (Leishmania infantum)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.94E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.23E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacylase sirtuin-5, mitochondrial (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent histone deacetylase SIR2 (Baker's yeast)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase (Leishmania infantum)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.94E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.45E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.03E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.03E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.92E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent histone deacetylase SIR2 (Baker's yeast)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.31E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Neutrophil elastase (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.23E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50156760 (2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair