BDBM50157493 4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol::CHEMBL222501::WAY-169916

SMILES Oc1ccc(-c2nn(CC=C)c3c(cccc23)C(F)(F)F)c(O)c1

InChI Key InChIKey=ZDUDMCQPFKPISO-UHFFFAOYSA-N

Data  3 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157493   

TargetEstrogen receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157493(4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]ben...)
Affinity DataIC50:  1.30E+3nMAssay Description:Displacement of [3H]E2 from ERalpha ligand binding domainMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157493(4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]ben...)
Affinity DataIC50:  106nMAssay Description:Displacement of [3H]E2 from ERbeta ligand binding domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157493(4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]ben...)
Affinity DataIC50:  93nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NFkappaB transcriptionMore data for this Ligand-Target Pair