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BDBM50157556 3-(3,4-dihydroxyphenyl)-1-(2,3,4-trihydroxyphenyl)prop-2-en-1-one::CHEMBL222557

SMILES: Oc1ccc(\C=C\C(=O)c2ccc(O)c(O)c2O)cc1O

InChI Key: InChIKey=GSBNFGRTUCCBTK-DAFODLJHSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157556   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Xanthine dehydrogenase


(Bos taurus (Bovine))
BDBM50157556
PNG
(3-(3,4-dihydroxyphenyl)-1-(2,3,4-trihydroxyphenyl)...)
Show SMILES Oc1ccc(\C=C\C(=O)c2ccc(O)c(O)c2O)cc1O
Show InChI InChI=1S/C15H12O6/c16-10(9-3-6-12(18)15(21)14(9)20)4-1-8-2-5-11(17)13(19)7-8/h1-7,17-21H/b4-1+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



Northern Kentucky University

Curated by ChEMBL


Assay Description
Inhibition of bovine xanthine oxidase assessed as conversion of xanthine to uric acid by spectroscopic analysis


Bioorg Med Chem 24: 578-87 (2016)


Article DOI: 10.1016/j.bmc.2015.12.024
BindingDB Entry DOI: 10.7270/Q23F4RJT
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50157556
PNG
(3-(3,4-dihydroxyphenyl)-1-(2,3,4-trihydroxyphenyl)...)
Show SMILES Oc1ccc(\C=C\C(=O)c2ccc(O)c(O)c2O)cc1O
Show InChI InChI=1S/C15H12O6/c16-10(9-3-6-12(18)15(21)14(9)20)4-1-8-2-5-11(17)13(19)7-8/h1-7,17-21H/b4-1+
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.00E+3n/an/an/an/an/an/a



BU-Nerviano Medical Sciences

Curated by ChEMBL


Assay Description
Inhibition of human telomerase from HEK293 cell extracts by Flash-Plate assay


J Med Chem 47: 6466-75 (2004)


Article DOI: 10.1021/jm040810b
BindingDB Entry DOI: 10.7270/Q2P55N1R
More data for this
Ligand-Target Pair