BDBM50157562 1,3-bis(3,4-dihydroxyphenyl)prop-2-en-1-one::3,3',4,4'-tetrahydroxychalcone::CHEMBL225618::US9085549, 94
SMILES Oc1ccc(\C=C\C(=O)c2ccc(O)c(O)c2)cc1O
InChI Key InChIKey=DOWSJIIZLUFMFM-DAFODLJHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50157562
Affinity DataKi: 1.10E+3nMpH: 7.4Assay Description:The compounds prepared in the preceding examples were found to bind with high affinity to α-synuclein aggregates/fibrils that are found in the h...More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Bu-Nerviano Medical Sciences
Curated by ChEMBL
Bu-Nerviano Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human telomerase from HEK293 cell extracts by Flash-Plate assayMore data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Northern Kentucky University
Curated by ChEMBL
Northern Kentucky University
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as conversion of xanthine to uric acid by spectroscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.14E+4nMAssay Description:The Thio S fluorometry assay as a primary screening method to identify tau protein aggregation inhibitors from our small molecule library. Aggregated...More data for this Ligand-Target Pair