BDBM50157570 4-cyano-N-(1,3-dimethyl-2-oxoquinolin-6-yl)-2-methoxybenzenesulfonamide::CHEMBL3752151::D0O6XT::GTPL8573::NI 57::NI-57::US11773085, Compound B26

SMILES: CC1=Cc2cc(ccc2N(C1=O)C)NS(=O)(=O)c3ccc(cc3OC)C#N

InChI Key: InChIKey=UEMQPCYDWCSVCU-UHFFFAOYSA-N

Data: 10 IC50  3 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50157570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 1 (Human)	BDBM50157570 (NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	619	n/a	n/a	n/a	n/a	7.4	25
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Bromodomain-containing protein 4 (Human)	BDBM50157570 (NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	25
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Peregrin (Human)	BDBM50157570 (NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	114	n/a	n/a	n/a	n/a	7.4	25
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Bromodomain and PHD finger-containing protein 3 (Human)	BDBM50157570 (NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	7.4	25
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Transcription intermediary factor 1-alpha (Human)	BDBM50157570 (NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	25
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Bromodomain-containing protein 9 [133-239] (Human)	BDBM50157570 (NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Bromodomain-containing protein 1 (Human)	BDBM50157570 (NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	315	n/a	n/a	n/a	n/a	n/a	n/a
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Bromodomain-containing protein 9 (Human)	BDBM50157570 (NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Peregrin (Human)	BDBM50157570 (NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
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Bromodomain and PHD finger-containing protein 3 (Human)	BDBM50157570 (NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 1 (Human)	BDBM50157570 (NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peregrin (Human)	BDBM50157570 (NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain and PHD finger-containing protein 3 (Human)	BDBM50157570 (NI-57 | D0O6XT | NI 57 | GTPL8573 | 4-cyano-N-(1,3...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair