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BDBM50158091 CHEMBL3780331

SMILES: OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)NCc1ccc(Cl)cc1

InChI Key: InChIKey=KRLITVFCQFXSTJ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50158091   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))
BDBM50158091
PNG
(CHEMBL3780331)
Show SMILES OC(=O)c1cc(c2ccccc2c1O)S(=O)(=O)NCc1ccc(Cl)cc1
Show InChI InChI=1S/C18H14ClNO5S/c19-12-7-5-11(6-8-12)10-20-26(24,25)16-9-15(18(22)23)17(21)14-4-2-1-3-13(14)16/h1-9,20-21H,10H2,(H,22,23)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.10E+4n/an/an/an/an/an/an/an/a



University of Maryland

Curated by ChEMBL


Assay Description
Inhibition of His6-MBP tagged recombinant human Mcl-1 residues 172 to 327 expressed in Escherichia coli assessed as inhibition of interaction with Ba...


Eur J Med Chem 113: 273-92 (2016)


Article DOI: 10.1016/j.ejmech.2016.02.006
BindingDB Entry DOI: 10.7270/Q2HX1FJH
More data for this
Ligand-Target Pair