BDBM50158154 CHEMBL3781784

SMILES NC(=N)c1cccc(c1)N1CC(O)CN(CC2CCN(Cc3ccccc3)CC2)C1=O

InChI Key InChIKey=HINXTEQWTTZJOH-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50158154   

TargetSerine protease hepsin(Homo sapiens (Human))
Southern Research

Curated by ChEMBL
LigandPNGBDBM50158154(CHEMBL3781784)
Affinity DataKi:  210nMAssay Description:Inhibition of human recombinant hepsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Southern Research

Curated by ChEMBL
LigandPNGBDBM50158154(CHEMBL3781784)
Affinity DataKi:  280nMAssay Description:Inhibition of human recombinant matripase catalytic domain using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Southern Research

Curated by ChEMBL
LigandPNGBDBM50158154(CHEMBL3781784)
Affinity DataKi:  390nMAssay Description:Inhibition of human recombinant trypsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Southern Research

Curated by ChEMBL
LigandPNGBDBM50158154(CHEMBL3781784)
Affinity DataKi:  850nMAssay Description:Inhibition of human recombinant factor 10a using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Southern Research

Curated by ChEMBL
LigandPNGBDBM50158154(CHEMBL3781784)
Affinity DataKi:  880nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Southern Research

Curated by ChEMBL
LigandPNGBDBM50158154(CHEMBL3781784)
Affinity DataKi:  2.19E+4nMAssay Description:Inhibition of human recombinant thrombin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed