BDBM50158460 (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone::2-ethyl-3-(3,5-dibrom-4-hydroxybenzoyl)benzofuran::3,5-dibromo-4-hydroxyphenyl-2-ethyl-3-benzofuranyl ketone::Benzbromarone::CHEMBL388590::US20240116873, Compound Benzbromarone::US9725430, Compound 1::US9856239, benzbromarone::US9962362, Compound 1::Uroleap (TN)::cid_2333

SMILES: CCc1c(c2ccccc2o1)C(=O)c3cc(c(c(c3)Br)O)Br

InChI Key: InChIKey=WHQCHUCQKNIQEC-UHFFFAOYSA-N

Data: 4 KI  58 IC50  2 Kd  5 EC50

PDB links: 5 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 73 hits for monomerid = 50158460   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transthyretin (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 12 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Solute carrier family 22 member 12 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Solute carrier family 22 member 12 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 6 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 2, facilitated glucose transporter member 9 (Mus musculus)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 12 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
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Transthyretin (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a
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cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 12 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
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Bile acid receptor (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.45E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
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Eyes absent homolog 3 [223-510] (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile salt export pump (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Polymerase acidic protein (Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.82E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cytochrome P450 2C9 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.92E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2J2 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cytochrome P450 2C9 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
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Monocarboxylate transporter 2 (Rat)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Monocarboxylate transporter 1 (Rat)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 12 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
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Multidrug resistance-associated protein 1 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member C1 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
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Sphingosine 1-phosphate receptor 1 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.94E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Solute carrier family 22 member 12 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
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Perilipin-5 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Perilipin-1 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Isoform 2 of Nuclear receptor corepressor 2 (TRAC-1) (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Photoreceptor-specific nuclear receptor (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
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M17 leucyl aminopeptidase (Plasmodium falciparum (isolate 3D7))	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Streptokinase A (Streptococcus pyogenes M1 GAS)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.72E+4	n/a	n/a	n/a	n/a
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M1 family aminopeptidase (Plasmodium falciparum (isolate FcB1 / Columbia))	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Inosine-5'-monophosphate dehydrogenase (Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sphingosine 1-phosphate receptor 1 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a
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Sphingosine 1-phosphate receptor 1 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.13E+3	n/a	n/a	n/a	n/a
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Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Eyes absent homolog 3 (Human)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Eyes absent homolog 3 [223-510] (Mouse)	BDBM50158460 (cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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