BDBM50158601 A-317920::CHEMBL361355::Furan-2-carboxylic acid ((R)-2-{4-[3-(4-cyclopropanecarbonyl-phenoxy)-propyl]-piperazin-1-yl}-1-methyl-2-oxo-ethyl)-amide

SMILES: C[C@@H](NC(=O)c1ccco1)C(=O)N1CCN(CCCOc2ccc(cc2)C(=O)C2CC2)CC1

InChI Key: InChIKey=RTRADBQSZJIRMT-UHFFFAOYSA-N

Data: 16 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50158601   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rat)	BDBM50158601 (CHEMBL361355 | A-317920 | Furan-2-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		0.631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Hrh3 protein (Rat)	BDBM50158601 (CHEMBL361355 | A-317920 | Furan-2-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		0.710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Rat)	BDBM50158601 (CHEMBL361355 | A-317920 | Furan-2-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		0.710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Hrh3 protein (Rat)	BDBM50158601 (CHEMBL361355 | A-317920 | Furan-2-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		0.720	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Guinea pig)	BDBM50158601 (CHEMBL361355 | A-317920 | Furan-2-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine receptor H3 (Dog)	BDBM50158601 (CHEMBL361355 | A-317920 | Furan-2-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		4.27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Human)	BDBM50158601 (CHEMBL361355 | A-317920 | Furan-2-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Human)	BDBM50158601 (CHEMBL361355 | A-317920 | Furan-2-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		93.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Human)	BDBM50158601 (CHEMBL361355 | A-317920 | Furan-2-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H3 receptor (Human)	BDBM50158601 (CHEMBL361355 | A-317920 | Furan-2-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM50158601 (CHEMBL361355 | A-317920 | Furan-2-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50158601 (CHEMBL361355 | A-317920 | Furan-2-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 3A (Rat)	BDBM50158601 (CHEMBL361355 | A-317920 | Furan-2-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM50158601 (CHEMBL361355 | A-317920 | Furan-2-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H2 receptor (Human)	BDBM50158601 (CHEMBL361355 | A-317920 | Furan-2-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H4 receptor (Human)	BDBM50158601 (CHEMBL361355 | A-317920 | Furan-2-carboxylic acid ...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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