BDBM50159141 CHEMBL3785343

SMILES CN(Cc1ccc(OC2CN(C2)C(=O)c2nnc(o2)-c2ccccc2)cc1)CC1(C)COC1

InChI Key InChIKey=GXBSBFLWQCTABZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50159141   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50159141(CHEMBL3785343)
Affinity DataIC50:  35nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cell membranes preincubated for 5 mins followed by addition of MCH peptide measured after 45 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50159141(CHEMBL3785343)
Affinity DataIC50:  14nMAssay Description:Displacement of [125I]Tyr13-MCH from mouse MCHR1 after 60 mins by microbeta scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50159141(CHEMBL3785343)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human ERG by IonWork assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed