BDBM50159210 4-Chloro-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol-5-yl)-benzenesulfonamide

SMILES Clc1ccc(cc1)S(=O)(=O)Nc1ccc2[nH]cc(CC3CCCN3)c2c1

InChI Key InChIKey=JPZREZRJDYDZQS-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50159210   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159210(4-Chloro-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol...)
Affinity DataKi:  3nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159210(4-Chloro-N-(3-(R)-1-pyrrolidin-2-ylmethyl-1H-indol...)
Affinity DataEC50:  4.5nMAssay Description:Effective agonist concentration in cAMP release assay in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed