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BDBM50159547 CHEMBL3786659

SMILES: [O-]C(=O)C(F)(F)F.CC[N+](CC)(CC)CCCS(=O)(=O)Nc1cc(cc(NC(=O)C(=O)c2ccc(OCCN3CCOCC3)c3ccccc23)c1OC)C(C)(C)C

InChI Key: InChIKey=RVZXVPBZKOUMNZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50159547   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Scavenger receptor class B member 1


(Homo sapiens (Human))
BDBM50159547
PNG
(CHEMBL3786659)
Show SMILES [O-]C(=O)C(F)(F)F.CC[N+](CC)(CC)CCCS(=O)(=O)Nc1cc(cc(NC(=O)C(=O)c2ccc(OCCN3CCOCC3)c3ccccc23)c1OC)C(C)(C)C
Show InChI InChI=1S/C38H54N4O7S.C2HF3O2/c1-8-42(9-2,10-3)21-13-25-50(45,46)40-33-27-28(38(4,5)6)26-32(36(33)47-7)39-37(44)35(43)31-16-17-34(30-15-12-11-14-29(30)31)49-24-20-41-18-22-48-23-19-41;3-2(4,5)1(6)7/h11-12,14-17,26-27,40H,8-10,13,18-25H2,1-7H3;(H,6,7)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 158n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human SR-B1 transiently expressed in human U2OS cells assessed as Dil-HDL uptake preincubated for 2 hrs followed by Dil-HDL addition me...


Bioorg Med Chem Lett 26: 1901-4 (2016)


Article DOI: 10.1016/j.bmcl.2016.03.025
BindingDB Entry DOI: 10.7270/Q22R3TJ2
More data for this
Ligand-Target Pair