BDBM50159612 2-Pyridin-4-yl-benzo[h]chromen-4-one::4-(4-Oxo-4H-benzo[h]chromen-2-yl)-pyridinium::CHEMBL177991::UCCF-029

SMILES O=c1cc(oc2c3ccccc3ccc12)-c1ccncc1

InChI Key InChIKey=LZCOBWKVDSSOBB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50159612   

TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50159612(2-Pyridin-4-yl-benzo[h]chromen-4-one | 4-(4-Oxo-4H...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of DNA dependent protein kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50159612(2-Pyridin-4-yl-benzo[h]chromen-4-one | 4-(4-Oxo-4H...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant CYP1A1 using 7-ethoxyresorufin as substrate in presence of glucose-6-phosphate, glucose-6-phosphate dehydrogenase and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50159612(2-Pyridin-4-yl-benzo[h]chromen-4-one | 4-(4-Oxo-4H...)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of human recombinant CYP1B1 using 7-ethoxyresorufin as substrate in presence of glucose-6-phosphate, glucose-6-phosphate dehydrogenase and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50159612(2-Pyridin-4-yl-benzo[h]chromen-4-one | 4-(4-Oxo-4H...)
Affinity DataIC50:  36nMAssay Description:Inhibition of human recombinant CYP1A2 using 7-ethoxyresorufin as substrate in presence of glucose-6-phosphate, glucose-6-phosphate dehydrogenase and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed