BDBM50159620 2-Morpholin-4-yl-pyrimido[2,1-a]isoquinolin-4-one::2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one::CHEMBL179242

SMILES: O=c1cc(nc2c3ccccc3ccn12)N1CCOCC1

InChI Key: InChIKey=BVRDQVRQVGRNHG-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50159620   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Human)	BDBM50159620 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
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Serine-protein kinase ATM (Human)	BDBM50159620 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase ATR (Human)	BDBM50159620 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50159620 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase mTOR (Human)	BDBM50159620 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Human)	BDBM50159620 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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DNA-dependent protein kinase catalytic subunit (Human)	BDBM50159620 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Human)	BDBM50159620 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one |...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair