BDBM50160154 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-(2,2,2-trifluoro-ethoxy)-phenoxy]-ethylamino}-propyl)-2,3-dihydro-1H-indole-7-carboxylic acid amide::CHEMBL24778::SILODOSIN

SMILES: C[C@H](Cc1cc2CCN(CCCO)c2c(c1)C(N)=O)NCCOc1ccccc1OCC(F)(F)F

InChI Key: InChIKey=PNCPYILNMDWPEY-UHFFFAOYSA-N

Data: 1 KI  15 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50160154   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1C (Human)	BDBM50160154 (CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.94E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50160154 (CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily D member 3 (Human)	BDBM50160154 (CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 5 subunit alpha (Human)	BDBM50160154 (CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily E/KQT member 1 (Human)	BDBM50160154 (CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.51E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50160154 (CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1D adrenergic receptor (Human)	BDBM50160154 (CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50160154 (CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Human)	BDBM50160154 (CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	541	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Rat)	BDBM50160154 (CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1D adrenergic receptor (Human)	BDBM50160154 (CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50160154 (CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Human)	BDBM50160154 (CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Rat)	BDBM50160154 (CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50160154 (CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50160154 (CHEMBL24778 | 1-(3-Hydroxy-propyl)-5-((R)-2-{2-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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