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BDBM50160724 3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl)-amino]-pyrrolidine-1-carboxylic acid methyl-[1-(tetrahydro-pyran-4-yl)-pyrrolidin-3-yl]-amide::CHEMBL436081

SMILES: CN(C1CCN(C1)C1CCOCC1)C(=O)N1CCC(C1)N(C)C(=O)c1ccc(cc1)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=LDJHHVNOOGLYRV-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160724   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM50160724
PNG
(3-[Methyl-(4''-trifluoromethyl-biphenyl-4-carbonyl...)
Show SMILES CN(C1CCN(C1)C1CCOCC1)C(=O)N1CCC(C1)N(C)C(=O)c1ccc(cc1)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1/C30H37F3N4O3/c1-34(28(38)23-5-3-21(4-6-23)22-7-9-24(10-8-22)30(31,32)33)26-12-16-37(20-26)29(39)35(2)27-11-15-36(19-27)25-13-17-40-18-14-25/h3-10,25-27H,11-20H2,1-2H3
Reactome pathway
KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
75n/an/an/an/an/an/an/an/a



Neurocrine Biosciences Inc.

Curated by ChEMBL


Assay Description
Displacement of [125I]MCH from human Melanin-concentrating hormone 1 (MCH1) receptor modified for optimal expression in HEK293 cells


Bioorg Med Chem Lett 15: 999-1004 (2005)


Article DOI: 10.1016/j.bmcl.2004.12.036
BindingDB Entry DOI: 10.7270/Q21R6R9X
More data for this
Ligand-Target Pair