BDBM50161274 CHEMBL3785696

SMILES COc1ccc(cc1)C(=O)CN2C(=O)C(NC2=O)(c3ccccc3)c4ccccc4

InChI Key InChIKey=BZIXIEVSXWQXTK-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50161274   

TargetProstaglandin G/H synthase 2(Sheep)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50161274(CHEMBL3785696)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of ovine COX2 assessed as reduction in PGH2-dervied PGF2alpha production preincubated for 5 mins followed by addition of arachidonic acid ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50161274(CHEMBL3785696)
Affinity DataIC50: 7.05E+4nMAssay Description:Inhibition of ovine COX1 preincubated for 5 mins followed by addition of arachidonic acid as substrate measured after 2 mins by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2017
Entry Details Article
PubMed