BDBM50161524 7-Phenyl-1-(5-pyridin-3-yl-[1,3,4]oxadiazol-2-yl)-heptan-1-one::CHEMBL361170

SMILES O=C(CCCCCCc1ccccc1)c1nnc(o1)-c1cccnc1

InChI Key InChIKey=KAZZIMTWPWCVEJ-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50161524   

TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50161524(7-Phenyl-1-(5-pyridin-3-yl-[1,3,4]oxadiazol-2-yl)-...)
Affinity DataKi:  1nMAssay Description:Inhibitor affinity of the compound towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50161524(7-Phenyl-1-(5-pyridin-3-yl-[1,3,4]oxadiazol-2-yl)-...)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50161524(7-Phenyl-1-(5-pyridin-3-yl-[1,3,4]oxadiazol-2-yl)-...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration of fatty acid amide hydrolase using FP-Rh radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50161524(7-Phenyl-1-(5-pyridin-3-yl-[1,3,4]oxadiazol-2-yl)-...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration of triacylgylcerol hydrolase using FP-Rh radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed