BDBM50161646 (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine::(R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine::CHEMBL360328::LORCASERIN

SMILES: C[C@H]1CNCCc2c1cc(cc2)Cl

InChI Key: InChIKey=XTTZERNUQAFMOF-UHFFFAOYSA-N

Data: 19 KI  50 EC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 69 hits for monomerid = 50161646   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	302	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	616	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	219	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Dog)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	16.2	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	943	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	478	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	943	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.60	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	794	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	258	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	328	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	328	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	258	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	245	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	433	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	437	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.10	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.10	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	248	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	59	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	158	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.90	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	79	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.80	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.80	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.92E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.60	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.60	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.60	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	437	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	59	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	433	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.40	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	248	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM50161646 ((R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	245	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair