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BDBM50161854 CHEMBL3794051

SMILES: CCCN(CCC)c1cccc2nc(Nc3c(C)cc(C)cc3C)n(C)c12

InChI Key: InChIKey=AROLCVGOMJTDQA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50161854   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))
BDBM50161854
PNG
(CHEMBL3794051)
Show SMILES CCCN(CCC)c1cccc2nc(Nc3c(C)cc(C)cc3C)n(C)c12
Show InChI InChI=1S/C23H32N4/c1-7-12-27(13-8-2)20-11-9-10-19-22(20)26(6)23(24-19)25-21-17(4)14-16(3)15-18(21)5/h9-11,14-15H,7-8,12-13H2,1-6H3,(H,24,25)
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MMDB

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Similars

Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Takeda Pharmaceutical Company Ltd.

Curated by ChEMBL


Assay Description
Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting method


J Med Chem 59: 2551-66 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01715
BindingDB Entry DOI: 10.7270/Q24F1SNR
More data for this
Ligand-Target Pair