BDBM50162213 1-methyl-1H-1,2,4-triazol-3-yl[6-phenyl-4,5,7,8-tetraazatetracyclo[9.2.2.02,10.03,7]pentadeca-2(10),3,5,8-tetraen-9-yloxy]methane::9-[(1-methyl-1H-1,2,4-triazol-3-yl)methoxy]-6-phenyl-4,5,7,8-tetraazatetracyclo[9.2.2.0^{2,10}.0^{3,7}]pentadeca-2(10),3,5,8-tetraene::CHEMBL366468
SMILES Cn1cnc(COc2nn3c(nnc3c3C4CCC(CC4)c23)-c2ccccc2)n1
InChI Key InChIKey=ZACQJMKEQBFUDN-UHFFFAOYSA-N
Data 8 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50162213
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp Laboratory
Curated by ChEMBL
Merck Sharp Laboratory
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]Ro-151788 from human recombinant GABAA alpha5 in combination with beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp Laboratory
Curated by ChEMBL
Merck Sharp Laboratory
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Inhibition of [3H]-Ro-15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2 subtype expressed in L (tk-) cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Inhibition of [3H]-Ro-15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 subtype expressed in L (tk-) cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Displacement of [3H]Ro-151788 from human recombinant GABAA alpha3 in combination with beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp Laboratory
Curated by ChEMBL
Merck Sharp Laboratory
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Displacement of [3H]-Ro15-1788 from human recombinant GABAA alpha2 in combination with beta3gamma2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp Laboratory
Curated by ChEMBL
Merck Sharp Laboratory
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Inhibition of [3H]-Ro-15-1788 binding to recombinant human gamma-aminobutyric acid A receptor alpha2-beta3-gamma2 subtype expressed in L (tk-) cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp Laboratory
Curated by ChEMBL
Merck Sharp Laboratory
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Displacement of [3H]-Ro15-1788 from human recombinant GABAA alpha1 in combination with beta-3-gamma-2 expressed in L(tk-) cellsMore data for this Ligand-Target Pair
Target InfoGoogleScholar
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp Laboratory
Curated by ChEMBL
Merck Sharp Laboratory
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Inhibition of [3H]-Ro-15-1788 binding to recombinant human gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 subtype expressed in L (tk-) cellsMore data for this Ligand-Target Pair
Target InfoGoogleScholar