BDBM50162310 CHEMBL178119::N*6*-Methyl-N*6*-(2,4,6-trimethoxy-benzyl)-quinazoline-2,4,6-triamine

SMILES COc1cc(OC)c(CN(C)c2ccc3nc(N)nc(N)c3c2)c(OC)c1

InChI Key InChIKey=URXVJLPACVARIO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50162310   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50162310(N*6*-Methyl-N*6*-(2,4,6-trimethoxy-benzyl)-quinazo...)
Affinity DataIC50: 950nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50162310(N*6*-Methyl-N*6*-(2,4,6-trimethoxy-benzyl)-quinazo...)
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50162310(N*6*-Methyl-N*6*-(2,4,6-trimethoxy-benzyl)-quinazo...)
Affinity DataIC50: 1.16E+5nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed