BDBM50162313 6-{[Methyl-(3,4,5-tris-methoxymethyl-phenyl)-amino]-methyl}-5,6,7,8-tetrahydro-quinazoline-2,4-diamine::CHEMBL178684

SMILES COCc1cc(cc(COC)c1COC)N(C)CC1CCc2nc(N)nc(N)c2C1

InChI Key InChIKey=VJFGAIISPFWMAS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50162313   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50162313(6-{[Methyl-(3,4,5-tris-methoxymethyl-phenyl)-amino...)
Affinity DataIC50: 330nMAssay Description:Inhibition of Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50162313(6-{[Methyl-(3,4,5-tris-methoxymethyl-phenyl)-amino...)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50162313(6-{[Methyl-(3,4,5-tris-methoxymethyl-phenyl)-amino...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed