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BDBM50162388 1-[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-piperazin-1-yl)-ethyl]-3-(4-trifluoromethyl-phenyl)-urea::CHEMBL373092

SMILES: CC(C)(C)c1ccc(cc1)C(CNC(=O)Nc1ccc(cc1)C(F)(F)F)N1CCN(CC1)C1CCCCC1

InChI Key: InChIKey=WVCVAYYNQLGCHZ-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162388   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162388
PNG
(1-[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-piperaz...)
Show SMILES CC(C)(C)c1ccc(cc1)C(CNC(=O)Nc1ccc(cc1)C(F)(F)F)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1/C30H41F3N4O/c1-29(2,3)23-11-9-22(10-12-23)27(37-19-17-36(18-20-37)26-7-5-4-6-8-26)21-34-28(38)35-25-15-13-24(14-16-25)30(31,32)33/h9-16,26-27H,4-8,17-21H2,1-3H3,(H2,34,35,38)
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PC cid
PC sid
UniChem

Similars

Article
PubMed
972n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair