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BDBM50162421 1-[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-piperazin-1-yl)-ethyl]-3-phenyl-urea::CHEMBL195427

SMILES: CC(C)(C)c1ccc(cc1)C(CNC(=O)Nc1ccccc1)N1CCN(CC1)C1CCCCC1

InChI Key: InChIKey=ZJTXGBBFIYXPJP-UHFFFAOYNA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162421   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C-C chemokine receptor type 3


(Homo sapiens (Human))
BDBM50162421
PNG
(1-[2-(4-tert-Butyl-phenyl)-2-(4-cyclohexyl-piperaz...)
Show SMILES CC(C)(C)c1ccc(cc1)C(CNC(=O)Nc1ccccc1)N1CCN(CC1)C1CCCCC1
Show InChI InChI=1/C29H42N4O/c1-29(2,3)24-16-14-23(15-17-24)27(22-30-28(34)31-25-10-6-4-7-11-25)33-20-18-32(19-21-33)26-12-8-5-9-13-26/h4,6-7,10-11,14-17,26-27H,5,8-9,12-13,18-22H2,1-3H3,(H2,30,31,34)
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UniProtKB/SwissProt
UniProtKB/TrEMBL

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.13E+3n/an/an/an/an/an/an/an/a



Biographics Laboratory 3R

Curated by ChEMBL


Assay Description
Inhibition of [125I]-eotaxin-1 binding to human chemokine receptor (hCCR3-C1)


J Med Chem 48: 1515-27 (2005)


Article DOI: 10.1021/jm040827u
BindingDB Entry DOI: 10.7270/Q2KK9B8W
More data for this
Ligand-Target Pair