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BDBM50162544 2-(2-Methoxy-phenyl)-3-phenethyl-3H-quinazolin-4-one::CHEMBL180383

SMILES: COc1ccccc1-c1nc2ccccc2c(=O)n1CCc1ccccc1

InChI Key: InChIKey=IHKNUWRYAXMVEM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162544   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calcium-sensing receptor (CaSR)


(Homo sapiens (Human))
BDBM50162544
PNG
(2-(2-Methoxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...)
Show SMILES COc1ccccc1-c1nc2ccccc2c(=O)n1CCc1ccccc1
Show InChI InChI=1S/C23H20N2O2/c1-27-21-14-8-6-12-19(21)22-24-20-13-7-5-11-18(20)23(26)25(22)16-15-17-9-3-2-4-10-17/h2-14H,15-16H2,1H3
PDB

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Similars

Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



NPS Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibitory concentration against human calcium receptor expressed in HEK 293 cells


Bioorg Med Chem Lett 15: 1557-60 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.078
BindingDB Entry DOI: 10.7270/Q22N51SD
More data for this
Ligand-Target Pair