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BDBM50162550 2-(3-Methoxy-phenyl)-3-phenethyl-3H-quinazolin-4-one::CHEMBL180136

SMILES: COc1cccc(c1)-c1nc2ccccc2c(=O)n1CCc1ccccc1

InChI Key: InChIKey=UOHMJVLBCWEIKM-UHFFFAOYSA-N

Data: 1 IC50

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Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162550   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Calcium-sensing receptor (CaSR)


(Homo sapiens (Human))
BDBM50162550
PNG
(2-(3-Methoxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...)
Show SMILES COc1cccc(c1)-c1nc2ccccc2c(=O)n1CCc1ccccc1
Show InChI InChI=1S/C23H20N2O2/c1-27-19-11-7-10-18(16-19)22-24-21-13-6-5-12-20(21)23(26)25(22)15-14-17-8-3-2-4-9-17/h2-13,16H,14-15H2,1H3
PDB

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PC sid
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Similars

Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



NPS Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibitory concentration against human calcium receptor expressed in HEK 293 cells


Bioorg Med Chem Lett 15: 1557-60 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.078
BindingDB Entry DOI: 10.7270/Q22N51SD
More data for this
Ligand-Target Pair