BDBM50162729 1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(thiophene-2-carbonyl)-[1,4]diazepane-2-carboxylic acid hydroxyamide::CHEMBL361809

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)c1cccs1

InChI Key InChIKey=AXPBXFSDSKBQDG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50162729   

TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162729(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(thiophene-2...)
Affinity DataIC50:  645nMAssay Description:Inhibitory concentration against matrix metalloproteinase-1 at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162729(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(thiophene-2...)
Affinity DataIC50:  142nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-13 at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162729(1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(thiophene-2...)
Affinity DataIC50:  10nMAssay Description:Inhibitory concentration against TNF-alpha converting enzyme at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed