BDBM50162774 ABT-199::US11420968, Example ABT-199::Venetoclax

SMILES: CC1(CCC(=C(C1)c2ccc(cc2)Cl)CN3CCN(CC3)c4ccc(c(c4)Oc5cc6cc[nH]c6nc5)C(=O)NS(=O)(=O)c7ccc(c(c7)[N+](=O)[O-])NCC8CCOCC8)C

InChI Key: InChIKey=LQBVNQSMGBZMKD-UHFFFAOYSA-N

Data: 33 KI  24 IC50  2 Kd  1 EC50

PDB links: 4 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 74 hits for monomerid = 50162774   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase NSD2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aspartyl/asparaginyl beta-hydroxylase (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aspartyl/asparaginyl beta-hydroxylase (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aspartyl/asparaginyl beta-hydroxylase (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aspartyl/asparaginyl beta-hydroxylase (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	705	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	157	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase, H3 lysine-36 specific (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase NSD3 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.240	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.340	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 [G101V] (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 [G101V] (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		<0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		<0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		<0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		<0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		<0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		<0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		<0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		<0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		<0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		<0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		<0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		0.0180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Human)	BDBM50162774 (ABT-199 | Venetoclax | US11420968, Example ABT-199) Show SMILES Show InChI	GoogleScholar	UniChem		1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair