BDBM50162816 CHEMBL180570::Medronic acid::Methylene diphsphonate::Phosphonomethyl-phosphonic acid::methylenediphosphonic acid

SMILES: C(P(=O)(O)O)P(=O)(O)O

InChI Key: InChIKey=MBKDYNNUVRNNRF-UHFFFAOYSA-N

Data: 9 KI  3 IC50

PDB links: 6 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50162816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Human)	BDBM50162816 (Medronic acid | methylenediphosphonic acid | Methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.25E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM50162816 (Medronic acid | methylenediphosphonic acid | Methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
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72 kDa type IV collagenase (Human)	BDBM50162816 (Medronic acid | methylenediphosphonic acid | Methy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Type IV secretion-like conjugative transfer relaxase protein TraI (Escherichia coli (strain SMS-3-5 / SECEC))	BDBM50162816 (Medronic acid | methylenediphosphonic acid | Methy...) Show SMILES Show InChI	GoogleScholar	UniChem		3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Fe(3+)-Zn(2+) purple acid phosphatase (Kidney bean)	BDBM50162816 (Medronic acid | methylenediphosphonic acid | Methy...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 5A, mitochondrial (Human)	BDBM50162816 (Medronic acid | methylenediphosphonic acid | Methy...) Show SMILES Show InChI	GoogleScholar	UniChem		7.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 9 (Human)	BDBM50162816 (Medronic acid | methylenediphosphonic acid | Methy...) Show SMILES Show InChI	GoogleScholar	UniChem		8.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM50162816 (Medronic acid | methylenediphosphonic acid | Methy...) Show SMILES Show InChI	GoogleScholar	UniChem		1.25E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 4 (Human)	BDBM50162816 (Medronic acid | methylenediphosphonic acid | Methy...) Show SMILES Show InChI	GoogleScholar	UniChem		5.34E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Ornithine transcarbamylase, mitochondrial (Human)	BDBM50162816 (Medronic acid | methylenediphosphonic acid | Methy...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	7.0	n/a
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Ornithine transcarbamylase, mitochondrial (Human)	BDBM50162816 (Medronic acid | methylenediphosphonic acid | Methy...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	6.0	n/a
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Ornithine transcarbamylase, mitochondrial (Human)	BDBM50162816 (Medronic acid | methylenediphosphonic acid | Methy...) Show SMILES Show InChI	GoogleScholar	UniChem		9.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	8.0	n/a
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