BDBM50162851 CHEMBL361545::[3-(1-{3-[5-Methanesulfonyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl]-propyl}-piperidin-4-yl)-2-oxo-2,3-dihydro-benzoimidazol-1-yl]-acetonitrile

SMILES CS(=O)(=O)N1CCc2c(C1)c(nn2CCCN1CCC(CC1)n1c2ccccc2n(CC#N)c1=O)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=AYROSXFGAMYUJP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162851   

TargetCathepsin S(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50162851(CHEMBL361545 | [3-(1-{3-[5-Methanesulfonyl-3-(4-tr...)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration against cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed